Whole Genome Sequencing of Four Representatives From the Admixed Population of the United Arab Emirates.

ABSTRACT: Whole genome sequences (WGS) of four nationals of the United Arab Emirates (UAE) at an average coverage of 33X have been completed and described. The selection of suitable subpopulation representatives was informed by a preceding comprehensive population structure analysis. Representatives were chosen based on their central location within the subpopulation on a principal component analysis (PCA) and the degree to which they were admixed. Novel genomic variations among the different subgroups of the UAE population are reported here. Specifically, the WGS analysis identified 4,161,067-4,798,806 variants in the four individual samples, where approximately 80% were single nucleotide polymorphisms (SNPs) and 20% were insertions or deletions (indels). An average of 2.75% was found to be novel v

SUBMITTER: Daw Elbait G 

PROVIDER: S-EPMC7367215 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature