Dataset Information

A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database.

ABSTRACT:

Background

This study aimed to establish a novel nomogram prognostic model to predict death probability for non-small cell lung cancer (NSCLC) patients who received surgery..

Methods

We collected data from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute in the United States. A nomogram prognostic model was constructed to predict mortality of NSCLC patients who received surgery.

Results

A total of 44,880 NSCLC patients who received surgery from 2004 to 2014 were included in this study. Gender, ethnicity, tumor anatomic sites, histologic subtype, tumor differentiation, clinical stage, tumor size, tumor extent, lymph node stage, examined lymph node, positive lymph node, type of surgery showed significant associations with lung cancer related death rate (P < 0.001). Patients who received chemotherapy and radiotherapy had significant higher lung cancer related death rate but were associated with significant lower non-cancer related mortality (P<0.001). A nomogram model was established based on multivariate models of training data set. In the validation cohort, the unadjusted C-index was 0.73 (95% CI, 0.72-0.74), 0.71 (95% CI, 0.66-0.75) and 0.69 (95% CI, 0.68-0.70) for lung cancer related death, other cancer related death and non-cancer related death.

Conclusions

A prognostic nomogram model was constructed to give information about the risk of death for NSCLC patients who received surgery.

SUBMITTER: Jia B

PROVIDER: S-EPMC7367407 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Publications

A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database.

Jia Bo B Zheng Qiwen Q Wang Jingjing J Sun Hongyan H Zhao Jun J Wu Meina M An Tongtong T Wang Yuyan Y Zhuo Minglei M Li Jianjie J Yang Xue X Zhong Jia J Chen Hanxiao H Chi Yujia Y Zhai Xiaoyu X Wang Ziping Z

BMC cancer 20200717 1

<h4>Background</h4>This study aimed to establish a novel nomogram prognostic model to predict death probability for non-small cell lung cancer (NSCLC) patients who received surgery..<h4>Methods</h4>We collected data from the Surveillance, Epidemiology, and End Results (SEER) database of the National Cancer Institute in the United States. A nomogram prognostic model was constructed to predict mortality of NSCLC patients who received surgery.<h4>Results</h4>A total of 44,880 NSCLC patients who rec ...[more]

PMID: 32680464

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Dataset Information

A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database.

Background

Methods

Results

Conclusions

Publications

A nomogram model to predict death rate among non-small cell lung cancer (NSCLC) patients with surgery in surveillance, epidemiology, and end results (SEER) database.

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