Outcomes of the Shunt Tube Exposure Prevention Study: A Randomized Clinical Trial.

ABSTRACT:

Purpose

To compare the long-term safety and efficacy of amniotic membrane-umbilical cord (AM-UC) and pericardium patch grafts in reducing glaucoma shunt tube exposure.

Design

Multicenter, prospective, randomized clinical trial.

Participants

Adults with uncontrolled glaucoma undergoing glaucoma drainage device (GDD) implantation.

Methods

Patients were randomized to receive GDD with either AM-UC or pericardium patch grafts to cover GDD tubes. Patients were followed up clinically with anterior segment (AS) OCT to assess patch graft stability and host-tissue integration prospectively.

Main outcome measures

Tube exposure, graft thinning, and graft-related complications.

Results

A total of 81 eyes of 81 patients (50 women, 31 men) with a mean age of 67±

SUBMITTER: Sheha H 

PROVIDER: S-EPMC7368089 | biostudies-literature | 2019 Nov - Dec

REPOSITORIES: biostudies-literature