Association between severity of obstructive sleep apnea and high-sensitivity C-reactive protein in patients with hypertrophic obstructive cardiomyopathy.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) is highly prevalent in patients with hypertrophic obstructive cardiomyopathy (HOCM). Inflammatory responses are increased in patients with OSA, meanwhile, inflammation is also associated with adverse outcomes in HOCM.

Hypothesis

To investigate the association between severity of OSA and high-sensitivity C-reactive protein (hs-CRP) in patients with HOCM.

Methods

Three hundred and ninteen patients with HOCM who underwent sleep evaluations at Fuwai Hospital were retrospectively included between February 2010 and December 2018. Data from baseline clinical characteristics and polysomnography studies were collected.

Results

OSA was present in 168 (52.7%). Patients with OSA were older, more likely to be male, had a higher body

SUBMITTER: Wang J 

PROVIDER: S-EPMC7368348 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature