Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents.

ABSTRACT:

Introduction

Exposures to volatile organic compounds and metals have previously been associated with liver diseases including steatohepatitis, although more data are needed. Benzene, toluene, ethylbenzene, xylenes, styrene (BTEXS) and metals were measured in blood samples collected between May 2012-July 2013 from volunteers participating in home visits for the Gulf Long-term Follow-up (GuLF) Study. This cross-sectional analysis evaluates associations of exposure biomarkers with serum liver injury and adipocytokine biomarkers in a sample of 214 men.

Methods

Adult nonsmoking men without a history of liver disease or heavy alcohol consumption were included. The serologic disease biomarkers evaluated were the hepatocellular injury biomarker, cytokeratin 18 [whole (CK18 M65) and

SUBMITTER: Werder EJ 

PROVIDER: S-EPMC7368391 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature