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From random to regular: Variation in the patterning of retinal mosaics.


ABSTRACT: The various types of retinal neurons are each positioned at their respective depths within the retina where they are believed to be assembled as orderly mosaics, in which like-type neurons minimize proximity to one another. Two common statistical analyses for assessing the spatial properties of retinal mosaics include the nearest neighbor analysis, from which an index of their "regularity" is commonly calculated, and the density recovery profile derived from autocorrelation analysis, revealing the presence of an exclusion zone indicative of anti-clustering. While each of the spatial statistics derived from these analyses, the regularity index and the effective radius, can be useful in characterizing such properties of orderly retinal mosaics, they are rarely sufficient for conveying the na

SUBMITTER: Keeley PW 

PROVIDER: S-EPMC7368823 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature