Insights into the antiviral activity of phospholipases A₂ (PLA₂s) from snake venoms.

ABSTRACT: Viruses are associated with several human diseases that infect a large number of individuals, hence directly affecting global health and economy. Owing to the lack of efficient vaccines, antiviral therapy and emerging resistance strains, many viruses are considered as a potential threat to public health. Therefore, researches have been developed to identify new drug candidates for future treatments. Among them, antiviral research based on natural molecules is a promising approach. Phospholipases A₂ (PLA₂s) isolated from snake venom have shown significant antiviral activity against some viruses such as Dengue virus, Human Immunodeficiency virus, Hepatitis C virus and Yellow fever virus, and have emerged as an attractive alternative strategy for the development of novel

SUBMITTER: Teixeira SC 

PROVIDER: S-EPMC7368918 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature