Differential chromatin accessibility landscape reveals structural and functional features of the allopolyploid wheat chromosomes.

ABSTRACT:

Background

Our understanding of how the complexity of the wheat genome influences the distribution of chromatin states along the homoeologous chromosomes is limited. Using a differential nuclease sensitivity assay, we investigate the chromatin states of the coding and repetitive regions of the allopolyploid wheat genome.

Results

Although open chromatin is found to be significantly enriched around genes, the majority of MNase-sensitive regions are located within transposable elements (TEs). Chromatin of the smaller D genome is more accessible than that of the larger A and B genomes. Chromatin states of different TEs vary among families and are influenced by the TEs' chromosomal position and proximity to genes. While the chromatin accessibility of genes is influenced by proxim

SUBMITTER: Jordan KW 

PROVIDER: S-EPMC7368981 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature