Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry.

ABSTRACT:

Background

The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the association between TyG index and coronary plaque progression (PP) using serial coronary computed tomography angiography (CCTA).

Methods

A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent serial CCTA with available data on TyG index and diabetic status were analyzed from The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry. PP was defined as plaque volume (PV) (mm³) at follow-up minus PV at index > 0. Annual change of PV (mm³/year) was defined as PV change divided by inter-scan period. Rapid PP was defined as the progressio

SUBMITTER: Won KB 

PROVIDER: S-EPMC7368987 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature