Assembly of the threespine stickleback Y chromosome reveals convergent signatures of sex chromosome evolution.

ABSTRACT:

Background

Heteromorphic sex chromosomes have evolved repeatedly across diverse species. Suppression of recombination between X and Y chromosomes leads to degeneration of the Y chromosome. The progression of degeneration is not well understood, as complete sequence assemblies of heteromorphic Y chromosomes have only been generated across a handful of taxa with highly degenerate sex chromosomes. Here, we describe the assembly of the threespine stickleback (Gasterosteus aculeatus) Y chromosome, which is less than 26 million years old and at an intermediate stage of degeneration. Our previous work identified that the non-recombining region between the X and the Y spans approximately 17.5 Mb on the X chromosome.

Results

We combine long-read sequencing with a Hi-C-based proximity

SUBMITTER: Peichel CL 

PROVIDER: S-EPMC7368989 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature