Tube Voltage, DNA Double-Strand Breaks, and Image Quality in Coronary CT Angiography.

ABSTRACT:

Objective

To evaluate the effects of tube voltage on image quality in coronary CT angiography (CCTA), the estimated radiation dose, and DNA double-strand breaks (DSBs) in peripheral blood lymphocytes to optimize the use of CCTA in the era of low radiation doses.

Materials and methods

This study included 240 patients who were divided into 2 groups according to the DNA DSB analysis methods, i.e., immunofluorescence microscopy and flow cytometry. Each group was subdivided into 4 subgroups: those receiving CCTA only with different tube voltages of 120, 100, 80, or 70 kVp. Objective and subjective image quality was evaluated by analysis of variance. Radiation dosages were also recorded and compared.

Results

There was no significant difference in demographic characteristics

SUBMITTER: Lin ZX 

PROVIDER: S-EPMC7369208 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature