Simultaneous Pre-Concentration and HPLC-MS/MS Quantification of Phycotoxins and Cyanotoxins in Inland and Coastal Waters.

ABSTRACT: The purpose of this study was to set up a sensitive method for the simultaneous determination of phycotoxins and cyanotoxins-Emerging pollutants with different structures and harmful properties (hepatotoxicity, neurotoxicity and cytotoxicity)-In environmental waters. Due to the low concentrations detected in these samples, a pre-concentration step is required and here it was performed in a single step with a commercial cartridge (Strata™-X), achieving enrichment factors up to 200 and satisfactory recovery (R = 70-118%) in different aqueous matrices. After solid-phase extraction (SPE), toxins were separated and quantified by High Performance Liquid Chromatography- Heated ElectroSpray Ionisation Tandem Mass Spectrometry (HPLC-HESI-MS/MS) in Multiple Reaction Monitoring (MRM) mode. An analyti

SUBMITTER: Merlo F 

PROVIDER: S-EPMC7369962 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature