Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study.

ABSTRACT:

Background

Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT). Herein, we hypothesized that local tirofiban infusion can be effective and safe for remnant stenosis in LVO during endovascular treatment and can improve clinical outcomes.

Methods

This observational multicenter registry study (January 2011 to February 2016) included patients with ICAS who underwent endovascular treatment for LVO within 24 h after stroke onset. An underlying fixed focal stenosis at the occlusion site observed on cerebral angiography during and after MT was retrospectively determined as a surrogate marker of ICAS. Procedural and clinical outcomes were compared be

SUBMITTER: Kim YW 

PROVIDER: S-EPMC7370431 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature