Comparative population genomic analysis uncovers novel genomic footprints and genes associated with small body size in Chinese pony.

ABSTRACT:

Background

Body size is considered as one of the most fundamental properties of an organism. Due to intensive breeding and artificial selection throughout the domestication history, horses exhibit striking variations for heights at withers and body sizes. Debao pony (DBP), a famous Chinese horse, is known for its small body size and lives in Guangxi mountains of southern China. In this study, we employed comparative population genomics to study the genetic basis underlying the small body size of DBP breed based on the whole genome sequencing data. To detect genomic signatures of positive selection, we applied three methods based on population comparison, fixation index (F_ST), cross population composite likelihood ratio (XP-CLR) and nucleotide diversity (θπ), and further

SUBMITTER: Asadollahpour Nanaei H 

PROVIDER: S-EPMC7370493 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature