Autonomic Modulation of Cardiac Arrhythmias: Methods to Assess Treatment and Outcomes.

ABSTRACT: The autonomic nervous system plays a central role in the pathogenesis of multiple cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. As such, autonomic modulation represents an attractive therapeutic approach in these conditions. Notably, autonomic modulation exploits the plasticity of the neural tissue to induce neural remodeling and thus obtain therapeutic benefit. Different forms of autonomic modulation include vagus nerve stimulation, tragus stimulation, renal denervation, baroreceptor activation therapy, and cardiac sympathetic denervation. This review seeks to highlight these autonomic modulation therapeutic modalities, which have shown promise in early preclinical and clinical trials and represent exciting alternatives to standard arrhythmia treatment. W

SUBMITTER: Stavrakis S 

PROVIDER: S-EPMC7370838 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature