Left Ventricular Mass and Incident Chronic Kidney Disease.

ABSTRACT: Chronic kidney disease (CKD) is associated with incident cardiovascular morbidity and mortality. Whether subclinical cardiovascular disease and target organ damage is associated with incident CKD is unknown. We investigated the relations of echocardiographic left ventricular mass (LVM) with incident CKD. We evaluated 2258 Framingham Offspring cohort participants (mean age, 57 years; 56% women) who underwent echocardiography at a routine examination and had an estimated glomerular filtration rate ≥60 mL/min per 1.73 m². We used Cox proportional hazards regression with discrete time intervals to relate sex-standardized LVM (independent variable) to the incidence of CKD, defined as estimated glomerular filtration rate <60 L/min per 1.73 m², on follow-up. During a median

SUBMITTER: Agarwal R 

PROVIDER: S-EPMC7370937 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature