CURatio: Genome-wide phylogenomic analysis method using ratios of total branch lengths.

ABSTRACT: Evolutionary hypotheses provide important underpinnings of biological and medical sciences, and comprehensive, genome-wide understanding of evolutionary relationships among organisms are needed to test and refine such hypotheses. Theory and empirical evidence clearly indicate that phylogenies (trees) of different genes (loci) should not display precisely matching topologies. The main reason for such phylogenetic incongruence is reticulated evolutionary history of most species due to meiotic sexual recombination in eukaryotes, or horizontal transfers of genetic material in prokaryotes. Nevertheless, many genes should display topologically related phylogenies, and should group into one or more (for genetic hybrids) clusters in poly-dimensional "tree space". Unusual evolutionary histories or

SUBMITTER: Kang Q 

PROVIDER: S-EPMC7372714 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature