Low-Dose Whole-Lung Irradiation for COVID-19 Pneumonia: Short Course Results.

ABSTRACT:

Purpose

The COVID-19 outbreak is affecting people worldwide. Many infected patients have respiratory involvement that may progress to acute respiratory distress syndrome. This pilot study aimed to evaluate the clinical efficacy of low-dose whole-lung radiation therapy in patients with COVID-19 pneumonia.

Methods and materials

In this clinical trial, conducted in Iran, we enrolled patients with COVID-19 who were older than 60 years and hospitalized to receive supplementary oxygen for their documented pneumonia. Participants were treated with whole-lung irradiation in a single fraction of 0.5 Gy plus the national protocol for the management of COVID-19. Vital signs (including blood oxygenation and body temperature) and laboratory findings (interleukin-6 and C-reactive peptide)

SUBMITTER: Ameri A 

PROVIDER: S-EPMC7373065 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature