Bioengineering Approaches for Corneal Regenerative Medicine.

ABSTRACT:

Background

Since the cornea is responsible for transmitting and focusing light into the eye, injury or pathology affecting any layer of the cornea can cause a detrimental effect on visual acuity. Aging is also a reason for corneal degeneration. Depending on the level of the injury, conservative therapies and donor tissue transplantation are the most common treatments for corneal diseases. Not only is there a lack of donor tissue and risk of infection/rejection, but the inherent ability of corneal cells and layers to regenerate has led to research in regenerative approaches and treatments.

Methods

In this review, we first discussed the anatomy of the cornea and the required properties for reconstructing layers of the cornea. Regenerative approaches are divided into two main c

SUBMITTER: Mahdavi SS 

PROVIDER: S-EPMC7373337 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature