Management of Pulmonary Arterial Hypertension in the Pediatric Patient.

ABSTRACT:

Purpose of review

Pediatric pulmonary arterial hypertension (PAH) is associated with significant morbidity and mortality. Herein we review the diagnosis and classification for pediatric PAH and detail the current therapeutic options available for use in the pediatric PAH population.

Recent findings

Classification and treatment of pediatric PAH is guided by adult criteria and treatment algorithms, yet the distribution of factors contributing to PAH in children differs significantly from that seen in adults. It is necessary to understand these differences in order to appropriately tailor therapy to the needs of the child or adolescent. An expanding array of targeted PAH drugs are now approved for use in adults, and many of these drugs are used "off-label" to treat children and

SUBMITTER: Ezekian JE 

PROVIDER: S-EPMC7373343 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature