Quality of clinical direct oral anticoagulant prescribing and identification of risk factors for inappropriate prescriptions.

ABSTRACT:

Aims

Even though the use of direct oral anticoagulants (DOACs) is safe based on clinical outcomes, drug safety also depends on appropriateness of drug prescription, which is challenging for DOACs since many patient factors need to be considered. The aim of this study was to assess the appropriateness of DOAC prescriptions and to identify risk factors of determinants for inappropriate DOAC prescriptions.

Methods

A retrospective study in a nonuniversity teaching hospital was performed of hospitalized patients (≥18 years) who received an initial DOAC prescription between February and August 2018. Appropriateness of prescribing was evaluated on 8 criteria by using a modified version of the medication appropriateness index.

Results

A total of 770 initial DOAC prescriptions

SUBMITTER: Zhang ZX 

PROVIDER: S-EPMC7373716 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature