Impacts of right ventricular function and venous congestion on renal response during depletion in acute heart failure.

ABSTRACT:

Aims

Venous congestion is a major determinant of worsening renal function (WRF) in acute decompensated heart failure (ADHF), particularly when associated with right ventricular (RV) dysfunction. Whether the individual impacts of hemodynamic variables on renal outcomes in ADHF is modified according to RV function remains unclear. We aimed to determine the association between hemodynamic parameters and early changes in renal function during depletive therapy and explore the association of these changes with clinical outcomes.

Methods and results

WRF was defined as any increase in creatinine after 24 h of depletive therapy and improvement in renal function (IRF) as any decrease. Assessments were prospectively obtained on admission, 24 h later and at discharge. Out of the 105 pa

SUBMITTER: Bouabdallaoui N 

PROVIDER: S-EPMC7373894 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature