The ventilatory abnormalities and prognostic values of H₂ FPEF score in dyspnoeic patients with preserved left ventricle systolic function.

ABSTRACT:

Aims

Heart failure with preserved ejection fraction (HFpEF) is one of the major diagnoses in dyspnoeic subjects, and H₂ FPEF score enables robust differentiation of HFpEF. Given ventilatory abnormalities prevail in subjects with HFpEF, the associations between H₂ FPEF score and pulmonary function remain to be elucidated.

Methods and results

Subjects who presented with exertional dyspnoea and had left ventricular ejection fraction of >50% were eligible for this study. Total lung capacity, forced expiratory volume in the 1 s, and forced vital capacity (FVC) were obtained by pulmonary function tests. Pulmonary artery systolic pressure (PASP), the ratio of early ventricular filling flow velocity to the septal mitral annulus tissue velocity (E/e'), and left

SUBMITTER: Huang WM 

PROVIDER: S-EPMC7373923 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature