Association of pulmonary hypertension and right ventricular function with exercise capacity in heart failure.

ABSTRACT:

Aim

Relationships of pulmonary artery systolic pressure (PASP) and right ventricular (RV) dysfunction with exercise capacity are understudied. To assess the relationship of PASP and RV function with functional capacity and ventilatory efficiency in heart failure (HF) with a wide range of left ventricular ejection fraction (LVEF).

Methods and results

Five hundred thirty-two consecutive HF patients referred for cardiopulmonary exercise testing [percent predicted peak VO₂ (ppVO₂ ), V_E /V_CO2 slope] and echocardiography [LVEF, PASP, and RV fractional area change (RVFAC)] were studied. Associations of PASP and RVFAC with ppVO₂ and V_E /V_CO2 slope were assessed by multivariable linear regression and restric

SUBMITTER: Teramoto K 

PROVIDER: S-EPMC7373932 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature