Plasma testosterone and arrhythmic events in male patients with arrhythmogenic right ventricular cardiomyopathy.

ABSTRACT:

Aims

Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with life-threatening ventricular arrhythmia and progressive ventricular dysfunction. Previous studies suggested that sex hormones play an important role in the onset and prognosis of ARVC. This study aimed to investigate the role of testosterone in predicting major adverse cardiac events in the Chinese ARVC cohort.

Methods and results

Ninety-nine ARVC patients (median age, 40 years; 70.7% male) and 96 healthy controls (median age, 41 years; 62.5% male) were enrolled. The circulating levels of testosterone were measured by enzyme-linked immunosorbent assays (ELISA). The median follow-up time of all ARVC male patients was 17 months (interquartile range/IQR 9-29). Cox proportional hazards regression was

SUBMITTER: Ren J 

PROVIDER: S-EPMC7373945 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature