Predicting sustained ventricular arrhythmias in dilated cardiomyopathy: a meta-analysis and systematic review.

ABSTRACT:

Aims

Patients with non-ischaemic dilated cardiomyopathy (DCM) are at increased risk of sudden cardiac death. Identification of patients that may benefit from implantable cardioverter-defibrillator implantation remains challenging. In this study, we aimed to determine predictors of sustained ventricular arrhythmias in patients with DCM.

Methods and results

We searched MEDLINE/Embase for studies describing predictors of sustained ventricular arrhythmias in patients with DCM. Quality and bias were assessed using the Quality in Prognostic Studies tool, articles with high risk of bias in ≥2 areas were excluded. Unadjusted hazard ratios (HRs) of uniformly defined predictors were pooled, while all other predictors were evaluated in a systematic review. We included 55 studies (11 45

SUBMITTER: Sammani A 

PROVIDER: S-EPMC7373946 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature