Helicobacter pylori Oncogenicity: Mechanism, Prevention, and Risk Factors.

ABSTRACT: Helicobacter pylori (H. pylori) is the most common cause of gastric ulcer; however, its association with gastric cancer has been proved through a variety of studies. Importantly, H. pylori infection affects around half of the world's population leading to a variety of gastric problems and is mostly present in asymptomatic form. Although about 20% of people infected with H. pylori develop preneoplastic gastric lesions in later stages of their life, around 2% of infected individuals develop gastric cancer. Nevertheless, the outcome of H. pylori infection is determined by complex interaction between the host genetics, its environment, and virulence factors of infecting strain. There are several biomarkers/traits of H. py

SUBMITTER: Muzaheed 

PROVIDER: S-EPMC7374235 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature