A comparative study to elucidate the biological activities of crude extracts from rice bran and wheat bran in cell line models.

ABSTRACT: The present study investigated the nutritional composition of bran from rice (RB) and wheat (WB) and compared the natural virtues of crude extracts based on phenolic composition, antidiabetic and anticancer activities. The profiling of phenolic-rich ethyl acetate extracts (RBE and WBE) confirms that RBE is rich in catechol (0.122 mg/g dw), p-coumaric acid (0.159 mg/g dw), kaempferol (0.374 mg/g dw) and apigenin (0.399 mg/g dw); and WBE is affluent with catechol (0.144 mg/g dw), ferulic acid (0.160 mg/g dw), caffeic acid (0.083 mg/g dw) and ellagic acid (0.074 mg/g dw). RBE exhibited better antioxidant activity, inhibited the activity of α-amylase (IC₅₀-353.41 µg/mL) and α-glucosidase (IC₅₀-314.22 µg/mL), hindered glycation process (IC₅₀-451.11 µg/mL)

SUBMITTER: Arun KB 

PROVIDER: S-EPMC7374552 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature