Longitudinal trends in perfluoroalkyl and polyfluoroalkyl substances among multiethnic midlife women from 1999 to 2011: The Study of Women's Health Across the Nation.

ABSTRACT:

Background

Limited information exists regarding longitudinal trends in midlife women's exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS). Further, little is known about how patterns of exposure differ by race/ethnicity and reproductive characteristics including parity and menopause.

Objective

We aimed to examine temporal variations in serum PFAS concentrations among midlife women from the Study of Women's Health Across the Nation.

Methods

Serum concentrations of 11 PFAS homologues were measured in 75 White, Black and Chinese women with blood samples collected in 1999-2000, 2002-2003, 2005-2006, and 2009-2011. Rates of changes in PFAS concentrations were calculated assuming a first-order elimination model. Associations between PFAS concentrations and rac

SUBMITTER: Ding N 

PROVIDER: S-EPMC7374929 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature