Metastable neural dynamics underlies cognitive performance across multiple behavioural paradigms.

ABSTRACT: Despite resting state networks being associated with a variety of cognitive abilities, it remains unclear how these local areas act in concert to express particular cognitive operations. Theoretical and empirical accounts indicate that large-scale resting state networks reconcile dual tendencies towards integration and segregation by operating in a metastable regime of their coordination dynamics. Metastability may confer important behavioural qualities by binding distributed local areas into large-scale neurocognitive networks. We tested this hypothesis by analysing fMRI data in a large cohort of healthy individuals (N = 566) and comparing the metastability of the brain's large-scale resting network architecture at rest and during the performance of several tasks. Metastability was estima

SUBMITTER: Alderson TH 

PROVIDER: S-EPMC7375112 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature