Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina.

ABSTRACT:

Background

From 1980 to 2017, a fluorochemical manufacturing facility discharged wastewater containing poorly understood per- and polyfluoroalkyl substances (PFAS) to the Cape Fear River, the primary drinking water source for Wilmington, North Carolina, residents. Those PFAS included several fluoroethers including HFPO-DA also known as GenX. Little is known about the bioaccumulation potential of these fluoroethers.

Objective

We determined levels of fluoroethers and legacy PFAS in serum samples from Wilmington residents.

Methods

In November 2017 and May 2018, we enrolled 344 Wilmington residents ≥6 years of age into the GenX Exposure Study and collected blood samples. Repeated blood samples were collected from 44 participants 6 months after enrollment. We analyzed seru

SUBMITTER: Kotlarz N 

PROVIDER: S-EPMC7375159 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature