A New Insight into the Surgical Treatment of Primary Macronodular Adrenal Hyperplasia.

ABSTRACT:

Purpose

This prospective study presents the results of a new approach in the treatment of primary macronodular adrenal hyperplasia (PMAH), with simultaneous total adrenalectomy of the larger adrenal gland and partial adrenalectomy of the contralateral adrenal gland (adrenal-sparing surgery).

Materials and methods

We performed a prospective study including 17 patients with PMAH treated surgically with adrenal-sparing surgery in a tertiary referral hospital, with a median follow-up of 41 months. Clinical, hormonal, and genetic parameters were evaluated before surgery and during follow-up. All patients had at least 1 radiological examination before and after the procedure.

Results

Among the 17 patients, all but 1 patient had complete hypercortisolism control, and 12 reco

SUBMITTER: Yoshiaki Tanno F 

PROVIDER: S-EPMC7375340 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature