Wool-derived keratin dressings versus usual care dressings for treatment of slow healing venous leg ulceration: a randomised controlled trial (Keratin4VLU).

ABSTRACT:

Objective

To determine the effect of a keratin dressing for treating slow-to-heal venous leg ulcers (VLU) on VLU healing.

Design

Pragmatic parallel group randomised controlled trial.

Setting

Community-dwelling participants.

Participants

People aged 18 or more years with VLU (either present for more than 26 weeks or ulcer area larger than 5 cm² or both).

Intervention

Wool-derived keratin dressing or usual care formulary of non-medicated dressings, on a background treatment with compression.

Primary and secondary outcome measures

Healing at 24 weeks based on blinded assessment of ulcer photographs. Other outcomes included time to complete healing, change in ulcer area to 24 weeks, change in health-related quality of life and incidence of

SUBMITTER: Jull A 

PROVIDER: S-EPMC7375503 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature