Modified lymph node ratio improves the prognostic predictive ability for breast cancer patients compared with other lymph node staging systems.

ABSTRACT:

Background

Metastatic regional lymph nodes (LN) is a strong predictor of worse long-term outcome. Therefore, different LN staging systems have been proposed in recent years. In this study, we proposed a modified lymph node ratio (mLNR) as a new lymph node staging system and then compared the prognostic performance of mLNR with American Joint Committee on Cancer N stage, lymph node ratio (LNR) and log odds of metastatic lymph nodes in breast cancer patients.

Methods

Breast cancer patients who underwent surgery between 2004 and 2012 were identified from the Surveillance, Epidemiology, and End Results database. Restricted cubic spline functions were calculated to characterize the association between variables and the risk of death. The Cox proportional hazards models were const

SUBMITTER: Jin ML 

PROVIDER: S-EPMC7375622 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature