Adverse effects information in clinical guidelines on pharmacological treatment of depression in children and adolescents: a systematic review.

ABSTRACT:

Objectives

To analyse to what extent clinical practice guidelines on drug treatment of depression in children and adolescents mention the risk of adverse effects, to characterise the citations in the guidelines and to assess to what extent data from a major study (Treatment for Adolescents With Depression Study, TADS) was used as basis for information about adverse effects.

Design

Systematic review of clinical guidelines and clinical decision support tools.

Data sources

PubMed, EMBASE, guideline collections, Health libraries.

Eligibility criteria

We included national guidelines on depression in children and adolescents from European and/or English-speaking countries, published in English, German, French or any Scandinavian language since 2008. We also included

SUBMITTER: Westergren T 

PROVIDER: S-EPMC7375629 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature