Effects of weight reduction on the breast cancer-related lymphedema: A systematic review and meta-analysis.

ABSTRACT:

Background

Obesity has long been considered a risk factor for breast cancer-related lymphedema (BCRL), but the benefits of weight reduction in managing BCRL have not been clearly established.

Objective

To evaluate the beneficial effects of weight loss interventions (WLIs) on the reduction and prevention of BCRL.

Methods

We conducted a systematic review and meta-analysis by searching the PubMed, Scopus, and Embase databases from their earliest record to October 1st, 2019. We included randomized and non-randomized controlled trials involving adult patients with a history of breast cancer, that compared WLI groups with no-WLI groups, and provided quantitative measurements of lymphedema.

Results

Initial literature search yielded 461 nonduplicate records. After excl

SUBMITTER: Tsai CL 

PROVIDER: S-EPMC7375642 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature