MR-based PET attenuation correction using a combined ultrashort echo time/multi-echo Dixon acquisition.

ABSTRACT:

Purpose

To develop a magnetic resonance (MR)-based method for estimation of continuous linear attenuation coefficients (LACs) in positron emission tomography (PET) using a physical compartmental model and ultrashort echo time (UTE)/multi-echo Dixon (mUTE) acquisitions.

Methods

We propose a three-dimensional (3D) mUTE sequence to acquire signals from water, fat, and short T₂ components (e.g., bones) simultaneously in a single acquisition. The proposed mUTE sequence integrates 3D UTE with multi-echo Dixon acquisitions and uses sparse radial trajectories to accelerate imaging speed. Errors in the radial k-space trajectories are measured using a special k-space trajectory mapping sequence and corrected for image reconstruction. A physical compartmental model is used t

SUBMITTER: Han PK 

PROVIDER: S-EPMC7375929 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature