Altered spatial summation optimizes visual function in axial myopia.

ABSTRACT: This study demonstrates significant differences between the area of complete spatial summation (Ricco's area, RA) in eyes with and without non-pathological, axial myopia. Contrast thresholds were measured for six stimuli (0.01-2.07 deg²) presented at 10º eccentricity in 24 myopic subjects and 20 age-similar non-myopic controls, with RA estimated using iterative two-phase regression analysis. To explore the effects of axial length-induced variations in retinal image size (RIS) on the measurement of RA, refractive error was separately corrected with (i) trial lenses at the anterior focal point (near constant inter-participant RIS in mm), and (ii) contact lenses (RIS changed with axial length). For spectacle corrected measurements, RA was significantly larger in the myopic group, w

SUBMITTER: Stapley V 

PROVIDER: S-EPMC7376210 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature