RRNPP-type quorum sensing affects solvent formation and sporulation in <i>Clostridium acetobutylicum</i>.

ABSTRACT: The strictly anaerobic bacterium Clostridium acetobutylicum is well known for its ability to convert sugars into organic acids and solvents, most notably the potential biofuel butanol. However, the regulation of its fermentation metabolism, in particular the shift from acid to solvent production, remains poorly understood. The aim of this study was to investigate whether cell-cell communication plays a role in controlling the timing of this shift or the extent of solvent formation. Analysis of the available C. acetobutylicum genome sequences revealed the presence of eight putative RRNPP-type quorum-sensing systems, here designated qssA to qssH, each consisting of an RRNPP-type regulator gene followed by a small open reading frame encoding a putative signalling p

SUBMITTER: Kotte AK 

PROVIDER: S-EPMC7376267 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature