An outbreak of acute respiratory infection at a training base in Beijing, China due to human adenovirus type B55.

ABSTRACT:

Background

Twelve students experienced symptoms of acute respiratory infection (ARI) at a training base in Beijing from August 26 to August 30, 2015. We investigated the cause of this ARI outbreak.

Methods

In partnership with the local center for disease control, we collected a total of twelve pharyngeal swab specimens as well as demographic information for the affected patients. We used multiplex real-time PCR to screen for sixteen common respiratory viruses in these samples. To isolate HAdV, we inoculated Hep-2 cells with the human adenovirus (HAdV)-positive samples and then carried out sequencing and phylogenetic analysis of the hexon, fiber, and penton genes of the isolated adenoviruses. In addition, we analyzed the entire genome of one strain isolated from the index cas

SUBMITTER: Lu G 

PROVIDER: S-EPMC7376533 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature