Protective Role of Bacterial Alkanesulfonate Monooxygenase under Oxidative Stress.

ABSTRACT: Bacterial alkane metabolism is associated with a number of cellular stresses, including membrane stress and oxidative stress, and the limited uptake of charged ions such as sulfate. In the present study, the genes ssuD and tauD in Acinetobacter oleivorans DR1 cells, which encode an alkanesulfonate monooxygenase and a taurine dioxygenase, respectively, were found to be responsible for hexadecanesulfonate (C₁₆SO₃H) and taurine metabolism, and Cbl was experimentally identified as a potential regulator of ssuD and tauD expression. The expression of ssuD and tauD occurred under sulfate-limited conditions generated during n-hexadecane degradation. Interestingly, expression analysis and knockout experiments suggested th

SUBMITTER: Park C 

PROVIDER: S-EPMC7376545 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature