Anidulafungin Versus Micafungin in the Treatment of Candidemia in Adult Patients.

ABSTRACT:

Background

Echinocandins are recommended for the treatment of invasive candidiasis and candidemia. However, there are few studies comparing anidulafungin and micafungin in terms of efficacy and safety. The objective of this study was to evaluate the clinical efficacy and safety between anidulafungin and micafungin treatment for adult patients with candidemia.

Methods

This retrospective cohort study performed on adult candidemia patients diagnosed from January 2006 through December 2018 at a tertiary medical center. The study subjects included adult patients ≥ 19 years with candidemia who were only treated with anidulafungin or micafungin for ≥ 3 days. Clinical characteristics were collected and analyzed. Hepatotoxicity was assessed according to the Common Terminology Criteri

SUBMITTER: Suh JW 

PROVIDER: S-EPMC7377311 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature