The Zebrafish Amygdaloid Complex - Functional Ground Plan, Molecular Delineation, and Everted Topology.

ABSTRACT: In mammals and other tetrapods, a multinuclear forebrain structure, called the amygdala, forms the neuroregulatory core essential for emotion, cognition, and social behavior. Currently, higher circuits of affective behavior in anamniote non-tetrapod vertebrates ("fishes") are poorly understood, preventing a comprehensive understanding of amygdala evolution. Through molecular characterization and evolutionary-developmental considerations, we delineated the complex amygdala ground plan of zebrafish, whose everted telencephalon has made comparisons to the evaginated forebrains of tetrapods challenging. In this radical paradigm, thirteen telencephalic territories constitute the zebrafish amygdaloid complex and each territory is distinguished by conserved molecular properties and structure-func

SUBMITTER: Porter BA 

PROVIDER: S-EPMC7378821 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature