Comparison of direct measurement of intracranial pressures and presumptive clinical and magnetic resonance imaging indicators of intracranial hypertension in dogs with brain tumors.

ABSTRACT:

Background

Intracranial hypertension (ICH) is often presumptively diagnosed based on clinical or imaging findings. Clinical or imaging surrogates of ICH are not usually validated with reference standard direct intracranial pressure (dICP) recordings.

Hypotheses

Dogs with brain magnetic resonance imaging (MRI) or clinical features of presumed ICH would have higher dICP than dogs lacking those features.

Animals

Twenty dogs with gliomas and 3 normal controls.

Methods

Prospective, convenience study. Dogs were presumptively categorized with normal ICP or ICH from scores generated from described clinical and brain MRI indicators of ICH. dICP was recorded in anesthetized dogs using an intraparenchymal microsensor and compared between groups.

Results

dICP was no

SUBMITTER: Giannasi S 

PROVIDER: S-EPMC7379039 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature