Investigation and Prediction of Human Interactome Based on Quantitative Features.

ABSTRACT: Protein is one of the most significant components of all living creatures. All significant and essential biological structures and functions relies on proteins and their respective biological functions. However, proteins cannot perform their unique biological significance independently. They have to interact with each other to realize the complicated biological processes in all living creatures including human beings. In other words, proteins depend on interactions (protein-protein interactions) to realize their significant effects. Thus, the significance comparison and quantitative contribution of candidate PPI features must be determined urgently. According to previous studies, 258 physical and chemical characteristics of proteins have been reported and confirmed to definitively affect t

SUBMITTER: Pan X 

PROVIDER: S-EPMC7379396 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature