The epidemiology of non-Candida yeast isolated from blood: The Asia Surveillance Study.

ABSTRACT:

Background

Current guidelines recommend echinocandins as first-line therapy for candidemia. However, several non-Candida yeast are non-susceptible to echinocandins (echinocandin non-susceptible yeast, ENSY), including Cryptococcus, Geotrichum, Malassezia, Pseudozyma, Rhodotorula, Saprochaete, Sporobolomyces and Trichosporon. In laboratories that are not equipped with rapid diagnostic tools, it often takes several days to identify yeast, and this may lead to inappropriate presumptive use of echinocandins in patients with ENSY fungemia. The aim of this study was to determine the distribution of ENSY species during a 1-year, laboratory surveillance programme in Asia.

Methods

Non-duplicate yeast isolated from blood or bone marrow cultures at 25 hospitals in China, Hong Kong, Ind

SUBMITTER: Lin SY 

PROVIDER: S-EPMC7379604 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature