Initial clinical experience with selective bladder denervation for refractory overactive bladder.

ABSTRACT:

Aims

To report the initial clinical experience with selective bladder denervation (SBD) of the trigone in women with refractory overactive bladder (OAB).

Methods

Females with refractory OAB underwent SBD of the bladder sub-trigone region. Patients were treated using a 10-s voltage-controlled radiofrequency (RF) algorithm (RF10) at study onset. The protocol was modified during the study after which point remaining patients received 60-s temperature-controlled RF (RF60). Patients were followed for 12 weeks and evaluated for adverse events and changes in OAB symptoms. Exploratory analyses on the influence of RF duration were performed.

Results

Among 63 patients, SBD resulted in statistically significant and clinically important improvements for most outcomes. Comparing R

SUBMITTER: Tu LM 

PROVIDER: S-EPMC7379657 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature