A systematic knowledge synthesis on the spatial dimensions of Q fever epidemics.

ABSTRACT: From 2007 through 2010, the Netherlands experienced the largest Q fever epidemic ever reported. This study integrates the outcomes of a multidisciplinary research programme on spatial airborne transmission of Coxiella burnetii and reflects these outcomes in relation to other scientific Q fever studies worldwide. We have identified lessons learned and remaining knowledge gaps. This synthesis was structured according to the four steps of quantitative microbial risk assessment (QMRA): (a) Rapid source identification was improved by newly developed techniques using mathematical disease modelling; (b) source characterization efforts improved knowledge but did not provide accurate C. burnetii emission patterns; (c) ambient air sampling, dispersion and spatial modelling promoted exposure assessme

SUBMITTER: De Rooij MMT 

PROVIDER: S-EPMC7379662 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature