International and Racial Differences in Mineral and Bone Disorder Markers and Treatments Over the First 5 Years of Hemodialysis in the Dialysis Outcomes and Practice Patterns Study.

ABSTRACT:

Rationale & objective

Normalization of parathyroid hormone (PTH), serum calcium, and phosphorus levels may prevent coronary and bone disease in hemodialysis (HD) patients. We describe the trajectory of these mineral bone disorder parameters and treatments during the first 5 years of HD by international region and race.

Study design

Prospective cohort study.

Setting & participants

33,517 US black/African American, US non-black/African American, European, and Japanese HD patients from the Dialysis Outcomes and Practice Patterns Study (DOPPS) phases 4 to 5 (2009-2015).

Predictor

Time since HD initiation.

Outcomes

Monthly cross-sections of mineral bone disorder parameters (PTH, serum calcium, and phosphorus) and medications (cinacalcet, active vitamin D, and

SUBMITTER: Chan K 

PROVIDER: S-EPMC7380354 | biostudies-literature | 2019 May-Jun

REPOSITORIES: biostudies-literature