Nonsurgical Periodontal Therapy in CKD: Findings of the Kidney and Periodontal Disease (KAPD) Pilot Randomized Controlled Trial.

ABSTRACT:

Rationale & objective

Observational studies have suggested that periodontal disease may be a modifiable risk factor for chronic kidney disease (CKD). The Kidney and Periodontal Disease (KAPD) Study was designed to determine the feasibility of conducting a periodontal disease treatment trial among a high-risk (mostly poor and racial/ethnic minority) population and estimate the magnitude and variability of kidney and inflammatory biomarker levels in response to intensive periodontal treatment.

Study design

Single-center, unmasked, intention-to-treat, randomized, controlled, pilot trial with 2:1 allocation to the treatment and comparison groups.

Setting & participants

English- and Spanish-speaking individuals aged 20 to 75 years receiving primary care within the San Fran

SUBMITTER: Grubbs V 

PROVIDER: S-EPMC7380373 | biostudies-literature | 2020 Jan-Feb

REPOSITORIES: biostudies-literature